대장균에서 목적 외래 단백질을 분비 생산하는 방법
대표분류 | 미생물/유전공학 | 구분 | 소액무상특허 |
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기술테마 | 미생물/유전공학 | ||
연구기관 | 한국과학기술연구원 | 연구자 | 판철호 |
기술내용 | 이전대상 특허번호: 8304210(미국) 이전유형: 양도 이전비용 : 1천만원 비고: 부가세별도 The present invention relates to a signal sequence peptide for the improvement of extracellular secretion efficiency of a heterologous protein in E. coli. More particularly, the present invention relates to a gene construct for the improvement of extracellular secretion efficiency of the said heterologous protein in E. coli, which comprises a polynucleotide encoding a recombinant protein composed of the heterologous protein linked to C-terminal of the signal sequence peptide represented by SEQ. ID. NO. 3. The present invention contributes to the improvement of extracellular secretion efficiency of a recombinant protein, so that it can be effectively applied to the production of a recombinant protein. |
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